- High resolution in vivo lung imaging of small animals.
- In vivo assessment of emphysema in mice.
- In vivo assesment and diagnosis of lung cancer in mice
 |  |
In vivo Micro-Computed Tomography of one mouse using four different imaging techniques, a) no gating, b) Late Inspiratory Gating, c) Late Expiratory Gating and finally d) Intermittent Iso-pressure Breath Hold (IIBH). Dosage constant between scans. ^ | In vivo 3D reconstruction of a mouse lung using the IIBH technique, with air fraction color coding. Using this precise in vivo gating scheme, individual lobes and lobar fissures are clearly visible. ^ |
 |  |
Respiratory gating system block diagram.(- - - -) dotted lines represent pneumatic | IIBH breathing sequence: hyperventilated breathing, two deep breaths (sighs) no ventilation, triggering of a forced airway pressure (breath hold), at which time the micro-CT is triggered and multiple angles of view are acquired.^ |
^ Namati, E., Chon, D., Thiesse, J., Hoffman, E. A., de Ryk, J., Ross, A., and McLennan, G., "In vivo micro-CT lung imaging via a computer-controlled intermittent iso-pressure breath hold (IIBH) technique," Phys Med Biol, vol. 51, pp. 6061-75, 2006.
©Copyright all rights reserved 2007,2008, Eman Namati.